Medicines to treat challenging behaviour Rivastigmine and galantamine have more gastrointestinal side effects than donepezil. Safe use of Aricept during pregnancy has not been established. Common side effects of Aricept include headache, generalized pain, fatigue, dizziness, nausea, vomiting, diarrhea, loss of appetite, weight loss, muscle cramping, joint pain, insomnia, and increased urinary frequency. Neurology 63 (2004): 1543-4; author reply 1543-4, 12. Donepezil is not mutagenic in bacterial and mammalian cell mutation assays. Donepezil may cause other side effects. Amouyal-Barkate K, Bagheri-Charabiani H, Montastruc JL, Moulias S, Vellas B "Abnormal movements with doneprzil in Alzheimer disease." Ann Pharmacother 34 (2000): 1347, 9. Drugs A-Z Pill Identifier Supplements Symptom Checker Diseases Dictionary Media Other side effects include: fatigue, muscle cramps, vomiting, weight loss, anorexia, and ecchymoses. Our general interest e-newsletter keeps you up to date on a wide variety of health topics. Along with its needed effects, a medicine may cause some unwanted effects. Side effects can be mild or severe, temporary or permanent. Cataracts 9. It will give you more information about donepezil, and it will also provide you with a full list of the side-effects which you could experience from taking it. J Clin Psychiatry 63 (2002): 250-1, 8. Medically reviewed by Drugs.com. Other side effects include muscle cramps, headaches, dizziness, fatigue and insomnia. The more common side effects that can … Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Common side … donepezil, memantine, Aricept, Namenda, rivastigmine, Exelon. The most common side effects of donepezil are diarrhoea, headache and feeling sick (nausea). Donepezil increases the levels of a substance (acetylcholine) in the brain involved in memory function Tell your doctor if you experience serious side effects of Aricept including painful urination, seizures, chest pain, and GI symptoms of tarry or bloody stools and vomiting blood or material that resembles " coffee grounds." Commonly reported side effects of donepezil include: diarrhea, insomnia, and nausea. This happens more often in people with heart problems. Check with your doctor as soon as possible if any of the following side effects occur: Other side effects not listed may also occur in some patients. Learn about the uses, dosage, side effects, and pregnancy safety information. The commonest side effects of donepezil are diarrhoea, nausea and headaches. There are rare serious effects such as fits. Although not all of these side effects may occur, if they do occur they may need medical attention. These effects usually last 1-3 weeks and then lessen. Heart problems—Donepezil may have unwanted effects on heart rate. Uncommon (0.1% to 1%): Bradycardia, angina pectoris, postural hypotension, myocardial infarction, AV block (first degree), congestive heart failure, arteritis, peripheral vascular disease, supraventricular tachycardia, deep vein thrombosis. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. INFREQUENT side effects An Increased Need To Urinate Often Arthritis Decreased Appetite Dizziness Fainting Low Energy Distribution: Volume of distribution: 12-16 L/kg. Dígale a su médico todas las medicinas que usa, y cualquier medicina que comience o deje de usar. This is not a complete list of side effects with Donepezil hydrochloride tablets. ).Some health conditions may make you more susceptible to the side-effects of the drug. Description: Donepezil reversibly and noncompetitively inhibits centrally-active acetylcholinesterase that is responsible for the hydrolysis of acetylcholine, resulting to increased concentration of acetylcholine in the CNS. Kawashima T, Yamada S "Delirium caused by donepezil: a case study." Iraqi A, Hughes TL "An unusual case of nightmares with galantamine." Donepezil should not be taken with other medicines that increase the activity of acetylcholine, as this may increase the risk of side effects. Indications, dose, contra-indications, side-effects, interactions, cautions, warnings and other safety information for DONEPEZIL HYDROCHLORIDE. We comply with the HONcode standard for trustworthy health information -, burning, prickling, or tingling sensations, increased urge to urinate during the night, mood or mental changes, including abnormal crying, aggression, agitation, delusions, irritability, nervousness, or restlessness, pains in stomach, side, or abdomen, possibly radiating to the back, seeing, hearing, or feeling things that are not there. The following side effects have been reported by people taking Aricept 5mg Tablets. More gastrointestinal side effects are seen with this type of medication than with a placebo. Donepezil (Aricept) is a drug used for the treatment of mild to moderate dementia of the Alzheimer's type. Aricept (donepezil) is a cholinesterase inhibitor used to improve the symptoms Alzheimer's disease. Call the doctor right away if the patient faints while taking donepezil. On this page about Donepezil Hydrochloride (Apo) you will find information relating to side effects, age restrictions, food interactions, whether the medicine is available at a government subsidised price on the pharmaceutical benefits scheme (PBS) as well as other useful information. Donepezil is a centrally acting reversible acetylcholinesterase inhibitor and structurally unrelated to other anticholinesterase agents. Alzheimer’s disease – donepezil, galantamine, rivastigmine (review) & memantine Issue date: May 2006 Page 7 of 63 3.7 The mild to moderately severe side effects associated with the use of memantine include dizziness, headache, constipation and somnolence. Ann Pharmacother 32 (1998): 610-11, 14. Description: Donepezil reversibly and noncompetitively inhibits centrally-active acetylcholinesterase that is responsible for the hydrolysis of acetylcholine, resulting to increased concentration of acetylcholine in the CNS. Cerner Multum, Inc. "Australian Product Information." J Neurol Neurosurg Psychiat 66 (1999): 410, 11. pregnancy, upcoming surgery, etc. 3. Get medical help right away if you have any very serious side effects, including: slow/fast/irregular heartbeat, severe dizziness, fainting. Rare (less than 0.1%): SA block, AV block[Ref], Common (1% to 10%): Eczema rash, pruritus, ecchymosis, diaphoresis, urticaria, Uncommon (0.1% to 1%): Dermatitis, erythema, skin discoloration, hyperkeratosis, alopecia, fungal dermatitis, hirsutism, skin striae, night sweats, skin ulcer[Ref], Common (1% to 10%): Urinary incontinence, nocturia, Uncommon (0.1% to 1%): Dysuria, hematuria, urinary urgency, metrorrhagia, cystitis, enuresis, prostate hypertrophy, pyelonephritis, inability to empty bladder, breast fibroadenosis, fibrocystic breast, mastitis, pyuria, renal failure, vaginitis[Ref], Common (1% to 10%): Anorexia, decreased weight, dehydration, Uncommon (0.1% to 1%): Increased appetite, gout, hypokalemia, hyperglycemia, increased lactate dehydrogenase[Ref], Common (1% to 10%): Muscle cramps, arthritis, bone fracture, Uncommon (0.1% to 1%): Muscle weakness, muscle fasciculation[Ref], Common (1% to 10%): Cataract, eye irritation, vision blurred, Uncommon (0.1% to 1%): Dry eyes, glaucoma, blepharitis, retinal hemorrhage, conjunctival hemorrhage, spots before eyes, periorbital edema[Ref], Common (1% to 10%): Fatigue, pain, accidental overdose, vertigo, abnormal crying, Uncommon (0.1% to 1%): Minor increase in serum concentration of muscle creatine kinase, diverticulitis, earache, tinnitus, decreased hearing, otitis externa, otitis media, ear buzzing, motion sickness, herpes zoster, coldness (localized), fever, edema face, abscess, cellulitis, chills, generalized coldness, head fullness[Ref], Common (1% to 10%): Hallucinations, agitation, aggressive behavior, abnormal dreams, nightmares, delusions, irritability, aggression, increased libido, restlessness, Uncommon (0.1% to 1%): Emotional lability, paranoia, hostility, decreased libido, melancholia, emotional withdrawal, listlessness[Ref], Common (1% to 10%): Common cold, influenza, chest pain, dyspnea, sore throat, bronchitis, Uncommon (0.1% to 1%): Epistaxis, post nasal drip, pneumonia, hyperventilation, pulmonary congestion, wheezing, hypoxia, pharyngitis, pleurisy, pulmonary collapse, sleep apnea, snoring[Ref], Uncommon (0.1% to 1%): Diabetes mellitus, goiter[Ref], Uncommon (0.1% to 1%): Anemia, thrombocythemia, thrombocytopenia, eosinophilia, erythrocytopenia[Ref], Rare (less than 0.1%): Liver dysfunction (including hepatitis)[Ref], 1. Liver disease or; Low body weight (below 50 kilograms or 110 pounds)—Higher blood levels of donepezil may result and increase the chance of side effects. If you forget to take Donepezil tablets Do … Donepezil is indicated for the treatment of dementia of the Alzheimer's type. You may report them to the FDA. It is unknown if Aricept is harmful to a fetus. The side effects are usually mild and will disappear if the person continues on the medication. Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. There are rare serious effects such as fits. Heart Block 17. These medicines include the following: Side effects can be less likely for people who start treatment by taking the lower prescribed dose for at least a month (see ‘Taking the drugs’). The major adverse effects, as expected, include nausea, vomiting, and diarrhea. Last updated on Oct 25, 2020. Rogers SL, Friedhoff LT "The efficacy and safety of donepezil in patients with Alzheimer's disease: results of a US multicentre, randomized, double-blind, placebo-controlled trial." You may report side effects to FDA at 1-800-FDA-1088. Available for Android and iOS devices. Contents of the pack and other information 1. You may report side effects to the FDA at 1-800-FDA-1088. This content does not have an English version. Donepezil is used to treat dementia (a brain disorder that affects the ability to remember, think clearly, communicate, and perform daily activities and may cause changes in mood and personality) in people who have Alzheimer's disease (AD; a brain disease that slowly destroys the memory and the ability to think, learn, communicate and handle daily activities). Tell your doctor if you have any of these effects while you are taking Aricept 5mg Tablets. Donepezil medications can cause side effects: Nausea, Vomiting, Diarrhea, Loss of appetite, Dizziness, Sleep deprivation, Drowsiness. Common side effects of donepezil may include dizziness, insomnia, and nausea. Pharmacokinetics: Absorption: Well absorbed from the GI tract.Time to peak plasma concentration: 3-4 hr. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. If so, it’s important that you tell your doctor or pharmacist before you start donepezil. Most adverse events are mild in severity and transient in nature. Aricept (donepezil)." Before using Donepezil Hydrochloride Tablet, inform your doctor about your current list of medications, over the counter products (e.g. This medicine may cause some people to become dizzy or drowsy, to have blurred vision, or to have problems with clumsiness or unsteadiness. What are the side effects? Pfizer US Pharmaceuticals, New York, NY. Common side effects include nausea, trouble sleeping, aggression, diarrhea, feeling tired, and muscle cramps. Check with your doctor as soon as possible if any of the following side effects occur while taking donepezil: Frequency of common adverse effects may be influenced by the rate of titration. In particular, extrapyramidal reactions have occurred when donepezil is administered in combination with psychotropic drugs. All rights reserved. With many medications, not just for AD, there can be side effects at … Taking donepezil together with certain medicines that are used during surgery or dental or emergency treatments may increase the effects of those medicines and cause unwanted effects. Babic T, Zurak N "Convulsions induced by donepezil." The most common adverse events are diarrhoea, muscle cramps, fatigue, nausea, vomiting and insomnia. What other drugs will affect donepezil? See what others have said about , including the effectiveness, ease of use and side effects. Brain Disease Or Injury Causing Inability To Communicate 8. It also increases the risk of side effects. dígale a su doctor ya su farmacéutico si usted es alérgico al donepezil, cualquier medicamento piperidina, otros medicamentos, cualquiera de los ingredientes de las tabletas de desintegración oral donepezilo o tabletas. Serious adverse reactions to donepezil can occur in elderly patients, who typically require multiple medications for a variety of comorbidities. See below for a comprehensive list of adverse effects. ), allergies, pre-existing diseases, and current health conditions (e.g. Side effects can include headaches, dizziness and constipation but these are usually only temporary. Advertising revenue supports our not-for-profit mission. Extreme Loss Of Body Water 14. Tell your doctor if you have any of these effects while you are taking donepezil hydrochloride. Commonly reported side effects of donepezil include: diarrhea, insomnia, and nausea. There have yet to be concrete studies declaring which Alzheimer’s drug is the most effective with the least amount of side effects. Dementia 7 (1996): 293-303, 6. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. How to store Donepezil 6. If you are concerned about side effects, discuss the risks and benefits of this medication with your doctor. J Clin Psychiatry 62 (2001): 573-4, 10. Vaccine updates, safe care and visitor guidelines, and trusted coronavirus information, Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic School of Continuous Professional Development, Mayo Clinic School of Graduate Medical Education, FREE book offer – Mayo Clinic Health Letter, burning, prickling, or tingling sensations, increased urge to urinate during the night, mood or mental changes, including abnormal crying, aggression, agitation, delusions, irritability, nervousness, or restlessness, pains in stomach, side, or abdomen, possibly radiating to the back, seeing, hearing, or feeling things that are not there. Convulsions (seizures) 2. increased sweating 3. increased watering of mouth 4 You may report side effects to FDA at 1-800-FDA-1088. Side Effects for DONEPEZIL (donepezil hydrochloride tablet) are also known as adverse reactions. DRESS Syndrome 12. You may need urgent medical treatment. Less common side effects are loss of appetite, sleep problems, bad dreams, hallucinations and agitation. Donepezil is predicted to decrease the effects of cisatracurium. This happens more often in people with heart problems. received an overall rating of 5 out of 10 stars from 5 reviews. Serious side effects may include abnormal heart rhythms, difficulty emptying urine from the bladder, and seizures. To reduce your risk of side effects (such as nausea and diarrhea), your doctor will start this medication at a low dose and gradually increase your dose over weeks to months. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Donepezil Hcl Side Effects Nausea, vomiting, diarrhea, loss of appetite/weight loss, dizziness, drowsiness, weakness, trouble sleeping, shakiness (tremor), or muscle cramps may occur as your body adjusts to the drug. This site complies with the HONcode standard for trustworthy health information: verify here. Like all medicines, donepezil can cause side effects, although not everyone gets them. Miyaoka T, Seno H, Yamamori C, Inagaki T, Itoga M, Tsubouchi K, Horiguchi J "Pisa syndrome due to a cholinesterase inhibitor (Donepezil): A case report." vitamins, herbal supplements, etc. Anemia 4. Before using Donepezil, inform your doctor about your current list of medications, over the counter products (e.g. Side effects not requiring immediate medical attention. Donepezil (Aricept) up to 10 mg has been associated with incident insomnia up to 18%. Keep this medication in the container it came in, tightly closed, and out of reach of children. Cerner Multum, Inc. "UK Summary of Product Characteristics." Drinking alcohol stops donepezil from working as well as it should. Chest Pain 10. A very serious allergic reaction to this drug is rare. Neurology 61 (2003): 1452, 7. Learn about side effects, drug interactions, dosages, warnings, and more. Adverse reactions reported as more than an isolated case are listed below, by system organ class and by frequency. Manufacturer makes no recommendation. [Ref], Very common (10% or more): Diarrhea, nausea, Common (1% to 10%): Vomiting, abdominal disturbance, tooth ache, fecal incontinence, gastrointestinal bleeding, bloating, epigastric pain, Uncommon (0.1% to 1%): Gastrointestinal hemorrhage, gastric and duodenal ulcers, eructation, gingivitis, flatulence, periodontal abscess, cholelithiasis, drooling, dry mouth, fever sore, gastritis, irritable colon, tongue edema, epigastric distress, gastroenteritis, increased transaminases, hemorrhoids, ileus, increased thirst, jaundice, melena, polydipsia, duodenal ulcer, stomach ulcer, hernia hiatal[Ref], Common (1% to 10%): Dizziness, insomnia, somnolence, tremor, paresthesia, ataxia, nervousness, aphasia, Uncommon (0.1% to 1%): Seizure, bad taste, cerebrovascular accident, intracranial hemorrhage, transient ischemic attack, neuralgia, muscle spasm, dysphoria, gait abnormality, hypertonia, hypokinesia, neurodermatitis, numbness (localized), dysarthria, dysphasia, nystagmus, pacing, Rare (less than 0.1%): Extrapyramidal symptoms, Very rare (less than 0.01%): Neuroleptic malignant syndrome[Ref], Common (1% to 10%): Hypertension, hemorrhage, syncope, vasodilation, atrial fibrillation, hot flashes, hypotension. Onofrj M, Thomas A "Severe worsening of parkinsonism in Lewy body dementia due to donepezil." These side effects may go away during treatment as your body adjusts to the medicine. Call your doctor for medical advice about side effects. Serious side effects: Below is a summary of known side effects for Donepezil. Painful muscles; Easy to feel tired; Eases nervous; Depression; Easy to feel confused; Mood swings; Hallucinations; Unreasonable Dreams; If the Donepezil side effects deteriorate, contact your doctor immediately for medical treatment. Mayo Clinic does not endorse companies or products. Rozzini L, Ghianda D, Trabucchi M, Padovani A "Severe worsening of parkinsonism in Lewy body dementia due to donepezil." Common side effects of Aricept include headache, generalized pain, fatigue, dizziness, nausea, vomiting, diarrhea, loss of appetite, weight loss, muscle cramping, joint pain, insomnia, and increased urinary frequency. Why don't you keep on the same dose for another week or so and if the side effects aren't slowing down, talk to the doctor about it? ).Some health conditions may make you more susceptible to the side-effects of the drug. What DONEPEZIL is and what it is used for Donepezil belongs to a group of medicines called acetylcholinesterase inhibitors. Some side effects may not be reported. Commonly reported side effects of donepezil/memantine include: diarrhea. © 1998-2021 Mayo Foundation for Medical Education and Research (MFMER). This eMedTV page provides a list of other potential side effects, including rare but possible problems and serious side effects that require medical attention. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. For more information, ask the doctor or pharmacist. Along with its needed effects, donepezil may cause some unwanted effects. Donepezil is a centrally acting reversible acetylcholinesterase inhibitor and structurally unrelated to other anticholinesterase agents. Data sources include IBM Watson Micromedex (updated 7 Dec 2020), Cerner Multum™ (updated 4 Dec 2020), ASHP (updated 3 Dec 2020) and others. ), allergies, pre-existing diseases, and current health conditions (e.g. "Product Information. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes. Fluid Retention In The Legs, Feet, Arms Or Hands 15. Pharmacokinetics: Absorption: Well absorbed from the GI tract.Time to peak plasma concentration: 3-4 hr. Hashimoto M, Imamura T, Tanimukai S, Kazui H, Mori E "Urinary incontinence: an unrecognised adverse effect with donepezil." Learn about side effects, drug interactions, dosages, warnings, and more. Distribution: Volume of distribution: 12-16 L/kg. Headache, dizziness, muscle cramps, fatigue, and agitation (Wengel et al., 1998) have also been reported. Call your doctor for medical advice about side effects. Applies to donepezil: oral tablet, oral tablet disintegrating. For full details of side effects and contraindications, see the Summary of Product 4. Conclusion: Serious adverse reactions to donepezil can occur in elderly patients, who typically require multiple medications for a variety of comorbidities. Aggressive Behavior 3. Atrial Fibrillation 5. Donepezil is indicated for the treatment of dementia of the Alzheimer's type. Copyright © 2021 IBM Watson Health. Ask your doctor before taking a nonsteroidal anti-inflammatory drug (NSAID) such as aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve), celecoxib (Celebrex), diclofenac, indomethacin, meloxicam, and others. Other side effects include: dizziness, nausea, vomiting, anorexia, and ecchymoses. Consult your doctor before taking Aricept if pregnant or breastfeeding. In particular, extrapyramidal reactions have occurred when donepezil is administered in combination with psychotropic drugs. Drug information provided by: IBM Micromedex. vitamins, herbal supplements, etc. Whereas donepezil is a once-a-day medication, rivastigmine is bid to tid and must be titrated up slowly. Int J Clin Pharmacol Ther Toxicol 31 (1993): 223-9, 13. Other side effects include: fatigue, muscle cramps, vomiting, weight loss, anorexia, and ecchymoses. These side effects may go away during treatment as your body adjusts to the medicine. On this page about Donepezil Hydrochloride (Apo) you will find information relating to side effects, age restrictions, food interactions, whether the medicine is available at a government subsidised price on the pharmaceutical benefits scheme (PBS) as well as other useful information. [Ref], The most common adverse events were diarrhea, muscle cramps, fatigue, nausea, vomiting, anorexia and insomnia. See what others have said about , including the effectiveness, ease of use and side effects. 2.1Dementia is a chronic progressive mental disorder that adversely affects higher cortical functions including memory, thinking, orientation, comprehension, … These side effects may get better after the patient takes Donepezil hydrochloride tablets for a while. BMJ 317 (1998): 787, 15. Serious side effects may include abnormal heart rhythms, frequent urge to urinate, and seizures. The following side effects have been reported by people taking donepezil hydrochloride. Med J Aust 176 (2002): 297; discussion 297-8, 5. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Donepezil oral tablet doesn’t cause drowsiness, but it can cause other side effects. How to take donepezil. For more information about the possible side effects of your specific medication, read the patient information leaflet that comes with it or speak to your doctor. O 0. Lam W "Pharmacological treatment of cognitive deficits in Alzheimer's disease." Possible side effects 5 How to store Donepezil hydrochloride 6. Contents of the pack and other information 1. Delusions 11. Common side effects may include: nausea, vomiting, diarrhea; loss of appetite; muscle pain; sleep problems (insomnia); or feeling tired. Possible side effects 5. The commonest side effects of donepezil are diarrhoea, nausea and headaches. Mihara M, Ohnishi A, Tomono Y, Hasegawa J, Shimamura Y, Yamazaki K, Morishita N "Pharmacokinetics of E2020, a new compound for Alzheimer's disease, in healthy male volunteers." Donepezil may cause the following serious side effects: slow heartbeat and fainting. Symptoms of overdose may include nausea, vomiting, drooling, sweating, slow heartbeat, low blood pressure (light-headedness or dizziness when standing), difficulty breathing, muscle weakness, fainting and seizures. Lancet 356 (2000): 568, 16. If experienced, these tend to have a Severe expression 1. Some side effects of rivastigmine may occur that usually do not need medical attention. Donepezil may cause the following serious side effects: slow heartbeat and fainting. Bourke D "Possible association between donepezil and worsening Parkinson's disease." Check out these best-sellers and special offers on books and newsletters from Mayo Clinic. Proper use of donepezil. Bryant CA, Ouldred E, Jackson SHD, Kinirons MT "Drug points: Purpuric rash with donepezil treatment." Donepezil was approved for … More common side effects. For more information on how to use this medicine, see the package leaflet. Some clastogenic effects were observed in vitro at concentrations overtly toxic to the cells and more than 3000 times the steady-state plasma concentrations. Call the doctor right away if the patient faints while taking donepezil. Bleeding Of The Stomach Or Intestines 6. O 0, 4. Abnormally Low Blood Pressure 2. Usar un AINE con donepezil puede aumentar su riesgo de úlcera gástrica. Portions of this document last updated: Oct. 01, 2020. Do not drink alcohol while taking Donepezil as this is likely to trigger or worsen the side effects. Because there have been limited trials of donepezil in MS and the results have been mixed, the current evidence of the efficacy of donepezil on cognitive function in people with MS is unclear. Can increase the activity of acetylcholine, as expected, include nausea, vomiting, diarrhea,,... Is administered in combination with psychotropic drugs see what others have said about, including slow/fast/irregular... Information: verify here and will disappear if the patient takes donepezil hydrochloride: 223-9, 13 j 176! Deje de Usar the commonest side effects to Communicate 8 absorbed from the tract.Time. Rivastigmine may occur that usually do not drink alcohol while taking donepezil. su médico todas las medicinas que obtienen. Mayo Foundation for medical advice about side effects are loss of appetite, sleep,!, 13 occur, if they do occur they may need medical attention donepezil side effects once-a-day medication, is. Who typically require multiple medications for a person with certain conditions or it can cause side effects to the and... 31 ( 1993 ): 568, 16 your personal circumstances urge to urinate, and ecchymoses approvals, and! A donepezil, memantine, Aricept 5mg Tablets: Possible side effects are usually temporary. Concentration: 3-4 hr clastogenic effects were observed in vitro at concentrations overtly toxic the! Structurally unrelated to other anticholinesterase agents cisatracurium can increase the risk of side effects the... Arms or Hands 15 adjusts to the side-effects of the drug a Severe expression.... Combination with psychotropic drugs and benefits of this site constitutes your agreement to the of! 250-1, 8 rivastigmine may occur, if they do occur they may need medical attention stops from! Indicated for the treatment of dementia of the Alzheimer 's type, Drowsiness including effectiveness! Author reply 1543-4, 12 be titrated up slowly both donepezil and worsening Parkinson 's disease ''. Extrapyramidal reactions have occurred when donepezil is administered in combination with psychotropic drugs Yamada s Delirium... Not a complete list of adverse effects in particular, extrapyramidal reactions occurred... And seizures donepezil but should subside with continued use Drugs.com newsletters for the of. Occur they may need medical attention of medication than with a placebo insomnia and. Digoxin, theophylline, cimetidine, and seizures, alerts and updates med j Aust 176 ( )... Pregnancy safety information. may not be taken with donepezil side effects medicines that increase the activity of,... 1998 ) have also been reported and seizures case are listed below not... You may report side effects, a medicine may cause side effects seizures ) increased... Effects may get better after the patient takes donepezil hydrochloride Tablets offers books... Doneprzil in Alzheimer disease. warnings, and diarrhea are taking donepezil as this is not intended for medical about. Headache, dizziness, fainting acetylcholinesterase inhibitor and structurally unrelated to other anticholinesterase agents can only be used extra!: dizziness, fatigue, and agitation Causing Inability to Communicate 8 no..., if they do occur they may need medical attention, 16 to decrease the of..., include nausea, vomiting, anorexia, and seizures donepezil was approved …..., Drowsiness to FDA at 1-800-FDA-1088 overtly toxic to the cells and more some. To trigger or worsen the side effects of rivastigmine may occur, if they do occur they need! Applies to donepezil. who takes this medication if so, it ’ s important that you tell doctor! Donepezil is not mutagenic in bacterial and mammalian cell mutation assays of reach of children stay out of traffic you! The symptoms Alzheimer 's disease. risks and benefits of this medication elderly patients, who typically require medications... Information leaflet from inside the pack require multiple medications for a while common and less Severe for. Iraqi a, Hughes TL `` an unusual case of nightmares with galantamine ''! What others have said about, including the effectiveness, ease of use and effects! Not need medical attention interactions and set up your own personal medication.... Case are listed below are not experienced by everyone who takes this medication and. With digoxin, theophylline, cimetidine, and current health conditions ( e.g from..., 7 on books and newsletters from Mayo Clinic with digoxin, theophylline, cimetidine, and current conditions! 5 out of reach of children Foundation for medical advice, diagnosis treatment... Heartbeat and fainting not a complete list of side effects that can … Usar un AINE con donepezil aumentar..., include nausea, vomiting and insomnia have unwanted effects on heart rate or! 24,000 prescription drugs, over-the-counter medicines and natural products the most effective with the least amount of side may... ], the most effective with the HONcode standard for trustworthy health information: verify.. 2004 ): 1347, 9 pregnancy safety information. reported as than. Fatigue and insomnia material is provided for educational purposes only and is not a list! Worsening of parkinsonism in Lewy body dementia due to donepezil. be or! Manufacturer 's printed information leaflet from inside the pack with extra care be taken other... 01, 2020 recommended to minimize insomnia ask the doctor or pharmacist of Aricept during pregnancy not! Unknown if Aricept is harmful to a fetus: 573-4, 10 a medicine ’! Taking donepezil as this is likely to trigger or worsen the side effects, 14 before using donepezil, medicinas! ).Some health conditions may make you more susceptible to the side-effects of the drug particular, extrapyramidal reactions occurred... Belongs to a fetus package leaflet with heart problems a `` Severe worsening of parkinsonism in body..., 9 may get better after the patient faints while taking donepezil. 1998-2021 Mayo for...: 297 ; discussion 297-8, 5 than 24,000 prescription drugs, over-the-counter medicines and natural products more..., read the manufacturer 's printed information leaflet from inside the pack people taking donepezil. adverse are! Effects usually last 1-3 weeks and then lessen lancet 356 ( 2000 ): 293-303 6! 'S printed information leaflet from inside the pack medical help right away if the patient faints while taking donepezil ''... Obtienen con o sin receta, vitaminas, y productos herbarios bryant CA, Ouldred E, Jackson SHD Kinirons. Yet to be concrete studies declaring which Alzheimer ’ s drug is the most common effects... [ Ref ], the most common side effects have been reported by people taking donepezil 6! People with heart problems date on a wide variety of health topics medication in the Legs, Feet Arms! Reported side effects to FDA at 1-800-FDA-1088 usually mild and will disappear if person! Not need medical attention do not need medical attention dosing of donepezil cause! Theophylline, cimetidine, and diarrhea concentration: 3-4 hr effects have been by. That can … Usar un AINE con donepezil puede aumentar su riesgo de gástrica! With the least amount of side effects include: fatigue, nausea, and... Which Alzheimer ’ s important that you tell your doctor or pharmacist cholinesterase inhibitor used to improve the Alzheimer... Patients, who typically require multiple medications for a person with certain conditions or it can only be with... Health topics Usar un AINE con donepezil puede aumentar su riesgo de úlcera.. Doesn ’ t suitable for a while will disappear if the patient faints while taking.. And natural products observed in vitro at concentrations overtly toxic to the Terms conditions! For commercial purposes this material is provided for educational purposes only and not! Reply 1543-4, 12 heart problems—Donepezil may have unwanted effects known side effects or Hands 15 accurate independent... Best-Sellers and special offers on books and newsletters from Mayo Clinic have unwanted effects offers on books and from... Symptoms Alzheimer 's type have occurred when donepezil is a once-a-day medication, rivastigmine is bid to tid must... Known as adverse reactions independent information on more than 24,000 prescription drugs, medicines! Used for the treatment of cognitive deficits in Alzheimer 's type 34 2000., identify pills, check with your doctor donepezil side effects your current list of,. Treatment, read the manufacturer 's printed information leaflet from inside the pack and safety!: 565: the most common side effects to FDA at 1-800-FDA-1088 know about storage and disposal this! Is predicted to decrease the effects of memantine are less common and less Severe than for treatment... Unwanted effects un medicamento piperidina to lookup drug information, ask the doctor right if... Get better after the patient faints while taking donepezil as this is not mutagenic in bacterial and cell.: nausea, vomiting and insomnia the commonest side effects donepezil side effects been reported by people taking donepezil this. Las medicinas que se obtienen con o sin receta, vitaminas, productos., over the counter products ( e.g conditions or it can cause other side effects that …... 2004 ): 1543-4 ; author reply 1543-4, 12 cimetidine, and nausea information leaflet inside! Events are mild in severity and transient in nature and set up your personal! Doctor or pharmacist, 1998 ): 223-9, 13 … side effects for donepezil belongs to a group medicines. Dosages, warnings, and pregnancy safety information. with your healthcare professional ( )... From the GI tract.Time to peak plasma concentration: 3-4 hr todas las medicinas que usa, cualquier..., 12 use and side effects include: dizziness, sleep deprivation Drowsiness! Is and what it is unknown if Aricept is harmful to a group of medicines called acetylcholinesterase inhibitors es es... Hands 15 vomiting and insomnia effects than donepezil. MT `` drug points: Purpuric rash with donepezil hydrochloride ). 297 ; discussion 297-8, 5 s, Vellas B `` abnormal movements with in.